Physical activity (PA) is beneficial for reducing all-cause mortality, and expert guidelines recommend consistent PA of at least 150 min/week of moderate-intensity or 75min/week of vigorous-intensity aerobic PA for adults. Continuing regular PA as recommended over time results in more survival benefits. Maintenance of body weight has also been reported to be associated with improved survival. A stable body weight is associated with decreased mortality risk, while weight variability is related to an increased risk of mortality.
These two factors are tightly intertwined. Physical activity plays an important role in body weight regulation, and weight gain is associated with future physical inactivity. Therefore, a change in PA and a change in body weight cannot be considered independently. However, how a continuing regular PA and maintaining body weight interact is not clear.
Although there were a few studies focusing on the combined effects of PA and body mass index (BMI) on mortality, no study clearly demonstrated any significant interactions. Therefore, the aim of the study is to elucidate whether continuing regular PA and maintaining body weight have interactions in terms of the risk of all-cause mortality.
This large population-based study demonstrated that continuing regular PA as recommended and maintaining body weight have multiplicative and additive interactions on reducing all-cause mortality. Healthcare providers should emphasize both continuing regular PA and body weight maintenance for the general public.
In this framework, Low or no physical activity is one of the behavioural risk factors identified by the YOUNG50 project for the Cardiovascular diseases.
The YOUNG50 project, through its Cardio50 screening programme, aims to affect cardiovascular risk factors, given to eight major CVD risk factors, fall into two groups:
Consult the study clicking HERE.
The MECKI score (Metabolic Exercise Cardiac Kidney Index) is based on an algorithm developed by the Centro Cardiologico Monzino (Italy), which will make it possible to assess the individual mortality risk of patients and consequently to identify the subjects most in need of treatment. The MECKI calculation is based on the values of the cardiopulmonary test together with other echocardiographic and laboratory parameters: haemoglobin, sodium, renal function, left ventricular ejection fraction, peak oxygen consumption and ventilatory efficiency under stress. This algorithm entered the clinical practice of cardiologists in Europe following its official introduction into the guidelines of the European Society of Cardiology (ESC). The calculator is available online and is also available in an iPad version, which can be downloaded free of charge from iTunes.
Know more: https://pubmed.ncbi.nlm.nih.gov/33238744/
The newsletter includes a presentation of the Animated Video that presents the YOUNG50 project and news about the launch of the screening activities in Romania and Lithuania.
In Romania the implementation of the screening activities for identification of behavioral and biological risk factors for cardio-vascular diseases included in the European project Young 50 have started in September 2021. The program is organised at local level through cooperation between NGO Aer Pur Romania, Iuliu Hatieganu University of Medicine and Pharmacy from Cluj-Napoca, Romania and Public Health Directorate of Cluj County, Romania.
Also in Lithuania on 25 September was launched the screening programme. Centro Poliklinika, Lithuanian partner of the project, from its patient database selected all 49-50 years old persons as potential participants and started with the screening activities.
Moreover, the newsletter includes news on the publication titled “Pandemic heightens the need to combat cardiovascular diseases” of the Lancet Regional Health Europe and on the launch from the European Commission of the “Health & healthy lifestyle” European-wide campaign.
Furthermore, information on the recent European initiatives are included. In fact, in the past few months the World Obesity Federation announced a new feature of its Global Obesity Observatory, “Presentation Maps”. Downloadable maps are available with survey-based prevalence data, obesity-related drivers & comorbidities, comparable estimated prevalence data, and more. Finally, the last September the European Alliance for Cardiovascular Health was launched during a policy debate attended by representatives of the European Commission, Member States and European Parliament. The main goal of this Alliance is to call for a comprehensive EU policy response to improve the cardiovascular health of European citizens.